---
title: In Vitro 3D Heart - Microtissue Model for Understanding Cardiotoxicity
description: Read our poster. 3D Microtissues for Detecting Functional and Structural Cardiotoxicity. Contact Evotec to learn more!
image: https://news.cyprotex.com/hubfs/Sciencepool/Sciencepool%20images/Shutterstock%20images/shutterstock_417318127-heart-blue-01-science-pool.jpg
---

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# Science Pool

# In Vitro 3D Heart - Microtissue Model for Understanding Cardiotoxicity

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 11, 2021 6:09:41 PM

*In vitro* 3D microtissue models are transforming our understanding of cardiotoxicity.

In this poster, we focus on:

- the use of a 3D cardiac triculture model consisting of iPSC-derived cardiomyocytes, cardiovascular endothelial cells and cardiac fibroblasts in cardiotoxicity prediction
- the detection of functional and structural mechanisms of cardiotoxicity
- calcium flux as a sensitive detection method for cardiac contraction as well as microtissue area for identifying cardiac hypertrophy
- HCS detection of cell health markers such as mitochondrial function, calcium homeostasis and nuclei/DNA structure

Read our poster to learn more about our research!

[LEARN MORE](https://news.cyprotex.com/hubfs/Sciencepool/3d-microtissue-cardiotoxicity-model-sot2018.pdf)

 

 

 

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