---
title: New Approaches in Toxicology - Takafumi Takai, Takeda
description: "hide gateway
Watch our webinar series to learn about new approaches in toxicology."
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---

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# Science Pool

# New Approaches in Toxicology - Takafumi Takai, Takeda

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Jan 27, 2022 11:06:25 AM

### **Understanding the Applicability and Limitations of *In Silico* and *In Vitro* Safety Models Towards the Design and Selection of the Safest Drug Candidates**

The second webinar in this series on New Approaches in Toxicology was presented by Takafumi Takai PhD from Takeda.

 

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### About the Webinar

 

A variety of *in silico* and *in vitro* safety assays are widely used in lead optimization in order to capture the safety-related liability as early as possible. Understanding the applicability and limitation of each assay based on the chemical space/chemotype is important for the effective usage. Several case studies of the applicability analysis including *in silico* phototoxicity prediction and low-dose *in vivo* toxicity prediction by cytotoxicity assay will be presented.

 

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### About the Speaker

 

| ![Takai Takafumi](https://news.cyprotex.com/hs-fs/hubfs/Takai%20Takafumi.png?width=257&name=Takai%20Takafumi.png) | **Takafumi Takai PhD** *Senior Scientist \| Takeda * Takafumi has more than 15 years of industry experience in drug discovery. He currently manages safety assessments mainly during compound optimization at Takeda California by using his expertise in medicinal and computational chemistry. Prior to joining the drug safety department, he led drug discovery projects as a medicinal chemist at Takeda in Japan. He holds a Ph.D. from Okayama University, Japan as well as a Master’s Degree from Tohoku University, Japan. |
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Watch the webinar to learn more!

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 Tags: [Videos & Webinars](https://news.cyprotex.com/sciencepool/tag/videos-webinars), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety)