Key Takeaways:
- We have developed an AI-generated antibody library platform, which we call J.HAL®, utilizing a Generative Adversarial Network (GAN) that generates novel sequences which mimic natural human response, as well biasing toward diversity and developability features.
- The resulting Humanoid Antibody Library was successfully screened to obtain a panel of novel, diverse and pharmacologically active human antibodies against SARS-CoV-2.