---
title: Cyclohexyl-Griselimycin is Active Against Mycobacterium Abscessus in Mice
description: "hide gateway
Read our publication! Cyclohexyl-Griselimycin is Active Against Mycobacterium Abscessusin Mice. Contact Evotec to learn more"
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---

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# Science Pool

# Cyclohexyl-Griselimycin is Active Against Mycobacterium Abscessus in Mice

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Jan 11, 2022 11:20:38 AM

Cyclohexyl-griselimycin is a preclinical candidate for tuberculosis (TB). In this recent article, we show that this oral cyclodepsipeptide is also active against the intrinsically drug resistant non-tuberculous *mycobacterium Mycobacterium abscessus* *in vitro* and in a mouse model of infection. This adds a novel advanced lead compound to the *M. abscessus* drug pipeline and supports a strategy of screening chemical matter generated in TB drug discovery efforts to fast track the discovery of novel antibiotics against *M. abscessus*

[LEARN MORE](https://journals.asm.org/doi/epdf/10.1128/AAC.01400-21)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [In vivo Pharmacology](https://news.cyprotex.com/sciencepool/tag/in-vivo-pharmacology), [Anti-Infectives](https://news.cyprotex.com/sciencepool/tag/anti-infectives)