Endocrine disruptors, which can be either natural or man-made, interfere with the normal actions of hormones in the body. This can result in serious health issues such as cancer, birth defects and developmental disorders. Low cost screening models are needed to flag chemicals as potential endocrine disruptors at an early stage.
In this poster, we focus on:
- the development of a new high throughput screening panel for chemicals to detect potential endocrine disruptors
- the comparison between endocrine receptor activation assays expressing the human androgen receptor, the human estrogen receptor or the human thyroid receptor, and hormone receptor competitor binding assays using fluorescence polarisation.
- the relationship between the literature and the data generated in the assays.
Read our poster to learn more about our research!