---
title: Mechanisms of Mitochondrial Toxicity - An In-depth Analysis using In Vitro Assays
description: Read our poster. Identifying Mechanisms of Mitochondrial Toxicity using In Vitro Assays. Contact Evotec to learn more!
image: https://news.cyprotex.com/hubfs/Sciencepool/Sciencepool%20images/Shutterstock%20images/shutterstock_396424405-mitochondria-blue-02-science-pool.jpg
---

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# Science Pool

# Mechanisms of Mitochondrial Toxicity - An In-depth Analysis using In Vitro Assays

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 11, 2021 8:39:36 PM

The mitochondria are a common target of drug-induced toxicity. A number of approaches are used to detect mitochondrial toxicity but how do we know which to use?

In this poster, we focus on:

- a comparison of the different methods including the glucose/galactose (glu/gal) cytotoxicity assay, high content screening (HCS) method for mitochondrial membrane potential and cytotoxicity, and the Seahorse flux analyser
- the ability of the different methods to predict mitochondrial toxicity through sensitivity, specificity and accuracy assessment
- an insight into the mechanism of mitochondrial toxicity through the Seahorse flux analyser and permeabilised cell assay.

Read our poster to learn more about our research!

[LEARN MORE](https://news.cyprotex.com/hubfs/Sciencepool/Posters/Cyprotex%20posters/Identifying-mechanisms-mitochondrial-toxicity-europeanWPC2018.pdf)

 

 

 Tags: [Posters](https://news.cyprotex.com/sciencepool/tag/posters), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety)