In order to accurately predict human pharmacokinetics and efficacious dose, a robust measurements of clearance is essential.
In this poster, we focus on:
- a novel primary human hepatocyte media supplement (HepExtendTM)
- a comparison of HepExtendTM with the widely used CM4000 with and without a Geltrex overlay
- a correlation of scaled in vitro human intrinsic clearance with in vivo human intrinsic clearance
Read our poster to learn more about our research!