Science Pool

Pilocarpine Neurotoxicity using MEA

Posted by Evotec on Feb 12, 2021 2:16:45 PM

Pilocarpine is a muscarinic receptor agonist, originally developed to treat dry mouth and glaucoma. It is also used to induce epilepsy in the rat. 

In this poster, we focus on:

  • pilocarpine response in vitro using MEA
  • analysis of the neuronal responses of different cell types such as cryopreserved rat cortical neurons, rat hippocampal neurons and human iPSC-derived glutamatergic neurons and astrocytes
  • the impact of cell maturation (DIV)

Read our poster to learn more about our research!

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Tags: Posters, Toxicology & Safety