Science Pool

Mass Defect Filtering for Metabolite Soft Spot ID

Posted by Evotec on Feb 12, 2021 2:33:07 PM

Real time mass defect filtering (MDF) on independent acquisition (IDA) scans enable the generation of simultaneous selective MS and MSMS data in one injection.

In this poster, we focus on:

  • the use of high resolution mass spectrometry and mass defect filtering combined with rapid chromatographic run times and semi-automated commercial software for soft-spot identification of metabolites
  • demonstration of the metabolite soft-spot method using verapamil and dextromethorphan

Read our poster to learn more about our research!

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Tags: Posters, ADME/DMPK