---
title: Neural Activity of the Muscarinic Receptor Agonist Pilocarpine
description: Read our poster. Neural Activity of Muscarinic Receptor Agonist Pilocarpine. Contact Evotec to learn more!
image: https://news.cyprotex.com/hubfs/Sciencepool/Sciencepool%20images/Shutterstock%20images/shutterstock_710281876-neuron-blue-03-science-pool.jpg
---

[![Cyprotex | The Leading ADME-Tox Specialist](https://news.cyprotex.com/hs-fs/hubfs/cyprotex%20logo.png?width=224&height=62&name=cyprotex%20logo.png "Cyprotex | The Leading ADME-Tox Specialist")](https://www.cyprotex.com/)

# Science Pool

# Neural Activity of the Muscarinic Receptor Agonist Pilocarpine

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 12, 2021 3:37:22 PM

Pilocarpine is a muscarinic receptor agonist which is used as a model inducer of epilepsy in the rat. We evaluated the seizurogenic response of pilocarpine using an* in vitro* MEA platform.

In this poster, we focus on:

- a comparison of pilocarpine response in different neuronal cell types; cryopreserved rat cortical neurons, cryopreserved rat hippocampal neurons and a co-culture of human iPSC-derived glutamatergic neurons with astrocytes
- the impact of DIV and cell maturation on the response
- identifying muscarinic receptor expression over time

Read our poster to learn more about our research!

[LEARN MORE](https://news.cyprotex.com/hubfs/Sciencepool/Posters/Cyprotex%20posters/Muscarinic-agonist-pilocarpine-neural-activity-sot2019.pdf)

 

 

 

 Tags: [Posters](https://news.cyprotex.com/sciencepool/tag/posters), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety)