---
title: PKPD Models for Antibiotic Efficacy
description: Read our poster. PKPD Modelling of Antibiotic Efficacy. Contact Evotec to learn more!
image: https://news.cyprotex.com/hubfs/Sciencepool/Sciencepool%20images/Inhouse%20images/cyprotex-inhouse-insilico-blue-01-science-pool.jpg
---

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# Science Pool

# PKPD Models for Antibiotic Efficacy

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 15, 2021 10:35:36 AM

Pharmacokinetic/pharmacodynamic (PK/PD) modelling plays an important role in drug development, especially in the case of antibiotics where the data generated is used for dose prediction up to Phase 2 clinical trials. This enables efficient study designs and identification of optimal dosing regimens that may suppress drug resistance.  

In this poster, we focus on:

- mathematical modelling of *in vivo* and *in vitro* data to generate a rational design with reduced animal requirements in order to determine the pharmacodynamic driver and magnitude of antibiotic efficacy
- optimisation of the clinical dose regimen in Phase 2 clinical trials

Read our poster to learn more about our research!

[LEARN MORE](https://news.cyprotex.com/hubfs/Sciencepool/Posters/Cyprotex%20posters/pkpd-modelling-antibiotic-efficacy-alderleypark3rs2018.pdf)

 

 Tags: [Posters](https://news.cyprotex.com/sciencepool/tag/posters), [In vivo Pharmacology](https://news.cyprotex.com/sciencepool/tag/in-vivo-pharmacology)