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title: Prediction of Functional and Structural Cardiotoxicants using hiPSC Cardiomyocytes
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Read our recent article- Prediction of Functional and Structural Cardiotoxicants using hiPSC Cardiomyocytes. Contact info@evotec.com to talk to our experts"
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# Science Pool

# Prediction of Functional and Structural Cardiotoxicants using hiPSC Cardiomyocytes

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Nov 29, 2023 11:08:22 AM

Cardiotoxicity remains one of the most reported adverse drug reactions that lead to drug attrition during pre-clinical and clinical drug development. Drug-induced cardiotoxicity may develop as a functional change in cardiac electrophysiology (acute alteration of the mechanical function of the myocardium) and/or as a structural change, resulting in loss of viability and morphological damage to cardiac tissue.

Our latest work, published in Expert Opinion on Drug Metabolism & Toxicology, is now available to download.

[Download](https://news.cyprotex.com/hubfs/Downloads/Articles%20and%20white%20papers/In-depth%20mechanistic%20analysis%20including%20high-throughput%20RNA%20sequencing%20in%20the%20prediction%20of%20functional%20and%20structural%20cardiotoxicants%20using%20hiPSC%20card.pdf)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety)