---
title: "Purkinje cells firing recorded by a high density multi-electrode array: a new tool for compounds validation"
description: "hide gateway
Read our poster. 3Brain high-density multi electrode array (HD-MEA) as a system to monitor and characterize seizure-like activity in hippo-cortical slices induced by different compounds. Contact Evotec to learn more."
image: https://news.cyprotex.com/hubfs/Sciencepool/Sciencepool%20images/Shutterstock%20images/shutterstock_1548861020-EPHYS_neuroscience2.jpg
---

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# Science Pool

# Purkinje cells firing recorded by a high density multi-electrode array: a new tool for compounds validation

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Jun 27, 2022 3:55:59 PM

This poster includes information about:

- Functional brain slice electrophysiology by HD-MEA platform
- Combined neuronal circuitry studies through functional brain tissue imaging

 Initially presented at FENS 2018 by Ugolini et al., 3Brain high-density multi electrode array (HD-MEA) as a system for long lasting monitor and characterize spiking activity of hundreds Purkinje cells simultaneously by using different positive and negative Ca++-activated K+ channels. Responses can be evaluated though different analysis. It is a useful tool for compounds validation on cerebellar slices.

[DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Posters/Evotec%20posters/HD-MEA-compounds-validation-purkinje-cells-firing-FENS2018-poster.pdf)

 Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Posters](https://news.cyprotex.com/sciencepool/tag/posters), [Hit & Target ID/Validation](https://news.cyprotex.com/sciencepool/tag/hit-target-id-validation), [In vitro Biology](https://news.cyprotex.com/sciencepool/tag/in-vitro-biology)