---
title: A Stereocontrolled Total Synthesis of Lipoxin B4 and its Biological Activity as a Pro-Resolving Lipid Mediator of Neuroinflammation
description: "hide gateway
Read our scientific article.  A Stereocontrolled Total Synthesis of Lipoxin B4 and its 
Biological Activity as a Pro-Resolving Lipid Mediator of 
Neuroinflammation. Contact info@evotec.com to learn more!"
---

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# Science Pool

# A Stereocontrolled Total Synthesis of Lipoxin B4 and its Biological Activity as a Pro-Resolving Lipid Mediator of Neuroinflammation

Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on May 25, 2022 4:19:02 PM

Originally published in Chemistry Europe.

A stereocontrolled and modular total synthesis of Lipoxin B4 (LXB4) was developed in 25% overall yield in just 10 steps. Previously reported syntheses to date were generally low yielding, together with long synthetic routes and lack full spectral characterization for LXB4. Download the article to learn more.

[DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Articles,%20DDups%20and%20Whitepapers/ChemistryAEuropeanJournal_StereoControlledTotalSynthesisOfLipoxinB4_2022.pdf)

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