---
title: | Events (5)
description: Events |  (5)
---

[![Cyprotex | The Leading ADME-Tox Specialist](https://news.cyprotex.com/hs-fs/hubfs/cyprotex%20logo.png?width=224&height=62&name=cyprotex%20logo.png "Cyprotex | The Leading ADME-Tox Specialist")](https://www.cyprotex.com/)

# Science Pool

## [AAPS PharmSci360 2023](https://news.cyprotex.com/sciencepool/aaps-pharmsci360-2023)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Sep 12, 2023 12:48:56 PM

Date: 22nd - 25th October 2023

Location: Orange County Convention Center - Orlando, FL

![Orlando_AdobeStock_617622107_rsz-1](https://news.cyprotex.com/hs-fs/hubfs/Orlando_AdobeStock_617622107_rsz-1.jpg?width=774&height=387&name=Orlando_AdobeStock_617622107_rsz-1.jpg)

Our team at AAPS PharmSci360

- Claudio Marcello Marzo, Associate Scientist • *In Vivo* Safety
- Pascale Clement, VP Pharmaceutical Development Science & Strategy • Pharmaceutical Development & Manufacturing
- Piero Piccinni, Senior Supervisor • Drug Product Manufacturing Operations
- Dhimant Patel, Senior Director • Business Development
- Michael Campognone, Senior Director • Business Development

Evotec will be exhibiting at booth #2935

| **[View our AAPS PharmSci360 scientific presentations](https://news.evotecsciencepool.com/aaps-pharmsci360-2023-evotec-posters-and-rapid-fire-presentations). Request your personal copy!** You will receive our four posters and two Rapid Fire presentations in your inbox right after the event.  |
| --- |

| **Our fully integrated solutions** Our CMC solutions are enhanced by the seamless integration of expertise and capabilities spanning from target identification to clinical development, including early and regulated ADME-Tox and safety pharmacology, regulatory support, clinical development & translational medicine: - Drug Substance & Drug Product Development from Lab Scale to Commercial Manufacturing - GMP Manufacturing of Small Molecules, Biologics, Cell Therapy Products - Early and Regulated ADME-Tox and Safety Pharmacology - Full Regulatory Support, Clinical Development & Translational Medicine (Phase 1/1b) Meet us at booth #2935 |
| --- |

 

[Learn more about Evotec at CPhI Barcelona and AAPS PharmSci360 2023](https://events.evotec.com/evotec-at-aaps-and-cphi-2023)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec)

## [iPSC-Derived Cell Therapies Summit 2023](https://news.cyprotex.com/sciencepool/ipsc-derived-cell-therapies-summit-2023)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Sep 12, 2023 11:35:30 AM

Date: 3rd - 4th October 2023

Location: Boston, MA, United States

Attending: Audrey Holtzinger, Vice President iPSC Cell Therapy, and Olivia Candini, Cell Therapy Process Development Supervisor

Evotec is Innovation Partner at this event. 

 

Oral and poster presentation

|   **Diabetes cell therapy with Evotec iPSC-derived islet-like clusters in the Sernova Cell PouchTM** *Presented by *Audrey Holtzinger, Vice President iPSC Cell Therapy, Evotec - Update on Evotec’s end-to-end integrated platform for iPSC-based cell therapeutics - Results from pre-clinical testing of iPSC-derived islet-like clusters combined with the implantable Cell Pouch *Oral presentation date and time: *October 4th, 2023, 2:30pm local *Session:* The Future is iPSCs: Re-Evaluating Translational & Strategical Priorities to Drive Next Steps Across the iPSC Industry   Development of an off-the-shelf allogenic anti-cancer cell therapy using potent iPSC-derived natural killer cells *Presented by *Audrey Holtzinger, Vice President iPSC Cell Therapy, Evotec *Poster presentation date and time: *October 3rd, 2023, 3:00pm local   |
| --- |

 

[Learn more about the iPSC-Derived Cell Therapies Summit 2023](https://ipsc-therapies-summit.com/)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec)

## [57th Congress of the European Societies of Toxicology - EuroTox](https://news.cyprotex.com/sciencepool/https/issx2023.org/-0)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Aug 24, 2023 1:49:27 PM

Date: 10th -13th September 2023

Location: GR - Ljubljana Exhibition and Convention Centre, Ljubljana Slovenia

Booth Location: 59

Attending: Ben Park, Alessandro Casartelli, Oksana Nikolayenko, Daniel Gliesche, Martin Augustin, Giuseppe D'Angelo & Rob Brown

Presentations

“Genotoxicity Risk Assessment during Lead Optimization Phase in Pharmaceutical Drug Development” - Presented by Alessandro Casartelli 

"Detection of Chemical Reactive Metabolites in a Glutathione depleted *in vitro *system" - Presented by Ben Park 

[Download: Bioactivation Driven Toxicity Product Sheet ](https://news.cyprotex.com/hubfs/Downloads/Fact%20sheets/Cyprotex_Bioactivation_Product_Sheet.pdf)

[Learn more about EuroTox 2023](https://www.eurotox2023.com/)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec), [Cyprotex](https://news.cyprotex.com/sciencepool/tag/cyprotex)

## [25th North American ISSX Meeting](https://news.cyprotex.com/sciencepool/https/issx2023.org/)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Jul 3, 2023 10:11:14 AM

Date: 10th -13th September 2023

Location: The Westin Boston Seaport District Boston, Massachusetts

Booth Location: 206

Attending: Stephen Madden, Chris Strock, Erin Koester, Ralf Geiben Lynn, Sravani Adusumalli, Li Li & Anu Marahatta

Presentation: : CYP46A1 Inhibition and Activation: An In Vitro High Throughput Screening Assay To Assess Possible Drug Interactions Using FDA Approved Chemical Library - Presented by Sravani Adusumalli & High Throughput and Fully Automated Sample Preparation for Quantitative Bioanalysis Using LC/MS/MS - Presented by Anu Marahatta

![](https://news.cyprotex.com/hs-fs/hubfs/ISSX+25+NA+MTNG+LOGO+-+COLOR@2x-png-1.png?width=398&height=249&name=ISSX+25+NA+MTNG+LOGO+-+COLOR@2x-png-1.png)

[Learn more about 25th North American ISSX Meeting](https://issx2023.org/)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Cyprotex](https://news.cyprotex.com/sciencepool/tag/cyprotex)

## [SMR-DMPK](https://news.cyprotex.com/sciencepool/https/www.smr.org.uk/meetings/20230706/programme.asp)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Jun 21, 2023 12:46:52 PM

Date: 06 July2023

Location: Alderley Park Conference Centre, Alderley Park, Congleton Road, Alderley Edge, Macclesfield SK10 4TG

Attending: Tim Potter, Mark Wenlock, Simon Thomas, Hannah Crowson, Stephen Madden & Phil Butler

Presentation: 1-3 The prediction of human pharmacokinetics in early-stage drug discovery - Simon Thomas

![](https://www.smr.org.uk/images/2018/SMR_New_Logo_2010.PNG)

[Learn more about SMR-DMPK](https://www.smr.org.uk/Meetings/20230706/programme.asp)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Cyprotex](https://news.cyprotex.com/sciencepool/tag/cyprotex)

## [Pharma Partnering US Summit 2022](https://news.cyprotex.com/sciencepool/pharma-partnering-us-summit)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Oct 17, 2022 10:50:22 AM

Date: 17 - 18 November, 2022

Venue: Encore Boston Harbor, Boston, MA

Attendees: Todd Ireland (Senior Director Business Development) and Cenk Cetin (VP Business Development)

 

Evotec and Just-Evotec Biologics will be attending the Pharma Partnering Summit in Boston, MA.

 

**If you wish to meet with us in Boston, get in touch via the form below, we will be happy to arrange a meeting.**

[Learn more about the Pharma Partnering US Summit](https://pharma-partnering-summit.com/us-event.html)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec)

## [Festival of Biologics](https://news.cyprotex.com/sciencepool/festival-of-biologics)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Oct 13, 2022 4:59:35 PM

Date: 2 - 4 November, 2022

Venue: Congress Centre, Basel, Switzerland

Attendees: Christelle Dagoneau (SVP Business Development), Thierry Wurch (SVP Integrated Biologics Discovery), and Nigel Shipston (Senior Director Business Development)

 

Evotec and Just-Evotec Biologics will be attending and presenting its science at the Festival of Biologics in Basel.

 

Our scientific program:

 

Presentation: Paradigm Shift in Biologics Manufacturing: Leveraging Continuous Manufacturing and AI/ML Based Technologies From Discovery to Market Supply

During this session, Christelle Dagoneau will present a unique platform concept which integrates the discovery, development, and manufacture of biologics in innovative and easily deployable production facilities called J.POD. She will particularly describe how the Just-Evotec Biologics cutting-edge AI/ML protein design technologies combined with industry-leading intensified continuous bioprocess can help de-risk and accelerate biotherapeutics development from lead generation through to BLA while offering cost-effective and truly flexible clinical and commercial supply solutions.

Presented by Christelle Dagoneau, SVP Business Development at Just-Evotec Biologics on 2 November at 17:10 CET

 

**Presentation: Evotec's Integrated Biologics Discovery and Development Platform to Strengthen Immunotherapy Research Programs**

At Evotec, we discover, develop and manufacture novel medicines for hard-to-treat diseases through efficient partnerships with academia, biotechs and pharma. Our discovery efforts focus on data-driven precision medicine and early disease relevance to improve success rates in identifying best-in-class therapeutics.

To support immunotherapy research projects, we developed an integrated discovery platform ranging from target validation, antibody discovery and optimization, in vitro/in vivo pharmacology, PK, and toxicology to select the best clinical candidates. By applying both humanized mouse-derived hybridoma and phage display coupled to AI/ML-based optimization, antibodies are selected based on disease relevant, target related in vitro and in vivo models. Applications for the identification of immune-modulating molecules will be discussed.

Presented by Theirry Wurch, SVP Integrated Biologics Discovery on 3 November at 17:20 CET

 

Poster: Conversion of an Intensified Fed-Batch to an Integrated Continuous Bioprocess

Despite advances in upstream and downstream Integrated Continuous Bioprocessing (ICB) technologies, reducing manufacturing costs and process development costs continue to be a concern.

Conversion of a fed-batch (FB) or intensified fed-batch (IFB) process into a hybrid or end-to-end ICB process may be particularly challenging but manageable using key platform elements: high specific productivity cell lines, low-cost, concentrated perfusion media formulations, an optimized and scalable cell-retention device, and the impact to product quality remains as a potential issue stemming from higher culture cell densities, longer culture durations, and differences in product residence times.

This work involved the rapid conversion of an IFB mAb process to a hybrid ICB process using the Just-Evotec Biologics platform, resulting in several key project accomplishments:

- Mitigation of upstream IFB challenges: Filter fouling due to higher culture cell densities and durations was addressed by controlling cell density and implementing continuous harvest (CH).
- Significant productivity increase: 5-fold increase in product mass per working volume compared to original FB process at the 500L manufacturing scale.
- Short development time: < 6 months from project start to cGMP batch completion.
- Minimal risk from changes in product quality: most attributes (HMW and rCE) and process impurities (HCP, DNA, and Pro-A) were comparable (minor differences in glycan distribution).
- These results demonstrate that the rapid conversion of FB and IFB mAb processes to ICB can be met when implementing a robust ICB platform, thus supporting the biotherapeutic industry’s need to quickly adapt to changing clinical and business circumstances.

 Presented by Nigel Shipston, Senior Director Business Developme

 

**If you wish to meet with us in Basel, get in touch via the form below, we will be happy to arrange a meeting.**

[Learn more about the Festival of Biologics](https://www.terrapinn.com/conference/festival-of-biologics/index.stm)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec)

## [5th European Cilia Conference](https://news.cyprotex.com/sciencepool/european-cilia-conference)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Sep 29, 2022 1:31:32 PM

Date: 4-7 October, 2022

Venue: Maternushaus, Cologne, Germany

Attendees: Priyanka Kohli (Research Scientist, Metabolic Diseases), Akanksha Dixit (Research Scientist, Metabolic Diseases), Kirsty Holden (Senior BD Executive – Attending Virtually)

 

Evotec will be sponsoring this year’s European Cilia conference as well as showcasing its research on site in Cologne. Come visit us in person at **booth #4**.

 

**If you wish to meet with us in Cologne, get in touch via the form below, we will be happy to arrange a meeting.**

[Learn more about the Cilia Conference.](https://www.cilia2022.de/)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec)

## [Southern California Chapter Fall 2022 Meeting](https://news.cyprotex.com/sciencepool/southern-california-chapter-fall-2022-meeting)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Sep 27, 2022 11:46:38 AM

Date: 06 October 2022

**Location: **Alexandria Point (Green Acres Campus Point, 10300 Campus Point Dr, San Diego, CA 92121)

Attendee: David Cerny

We hope to see you at Southern California Chapter Fall 2022 Meeting!

[Learn more about Southern California Chapter Fall 2022 Meeting](https://www.toxicology.org/groups/rc/SouthernCal/events.asp)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Cyprotex](https://news.cyprotex.com/sciencepool/tag/cyprotex)

## [BioRN Annual Conference](https://news.cyprotex.com/sciencepool/biorn-annual-conference-2022)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Sep 20, 2022 5:35:23 PM

Date: 7 October 2022

Venue: Heidelberg, Germany

Attendees: Friedrich Reinhard (VP Academic Partnerships) and Laurie Sarrat (Business Development Manager)

 

Evotec will be attending at this year’s BioRN Annual conference  as well as showcasing its research on site in Heidelberg.

 

**If you wish to meet with us in Heidelberg, get in touch via the form below, we will be happy to arrange a meeting.**

[Learn more about the BioRN Annual Conference](https://www.biorn.org/biorn-annual-conference)

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 Tags: [Events](https://news.cyprotex.com/sciencepool/tag/events), [Evotec](https://news.cyprotex.com/sciencepool/tag/evotec)

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