--- title: | Neuroscience (5) description: Neuroscience | (5) --- [![Cyprotex | The Leading ADME-Tox Specialist](https://news.cyprotex.com/hs-fs/hubfs/cyprotex%20logo.png?width=224&height=62&name=cyprotex%20logo.png "Cyprotex | The Leading ADME-Tox Specialist")](https://www.cyprotex.com/) # Science Pool ## [Neurodegenerative Diseases DDup #2](https://news.cyprotex.com/sciencepool/neurodegenerative-diseases-ddup-2) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 16, 2021 10:31:50 PM 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/neurodegenerative-diseases-ddup-2#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers) ## [Evaluating Pharmacology and Neurotoxicity using MEA](https://news.cyprotex.com/sciencepool/pharmacology-neurotoxicity-using-mea-sps2017) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 12, 2021 3:46:13 PM Advances in human iPSC-derived neuronal models in conjunction with microelectrode array (MEA) technology has enhanced our understanding of complex burst organisation and network characteristics in humans. This now provides a viable human model for studying drug-induced toxicity and CNS liabilities as well as potential pharmacology effects on the neurones. In this poster, we focus on: - investigating co-cultures of human iPSC-derived glutamatergic neurons with astrocytes on the MEA platform - determining spike activity, burst organisation and network organisation (synchrony) patterns for different types of CNS compounds (GABAA agonists, potassium channel blockers, opioid receptor agonist, glycine receptor antagonist and cholinergic and muscarinic receptor agonists) - understanding developmental and pharmacological responses when assessed by MEA Read our poster to learn more about our research! [LEARN MORE](https://news.cyprotex.com/hubfs/Sciencepool/Posters/Cyprotex%20posters/Pharmacology-and-neurotoxicity-ipsc-mea-sps2017.pdf)     0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/pharmacology-neurotoxicity-using-mea-sps2017#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Posters](https://news.cyprotex.com/sciencepool/tag/posters), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety) ## [Proteome Analysis of Huntington's Disease Fact Sheet](https://news.cyprotex.com/sciencepool/proteome-analysis-of-huntingtons-disease-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 12, 2021 2:05:00 PM Download this fact sheet to learn more about Huntington's Disease proteome base including:  - Strains and collection of tissues - Deep proteome workflow - Key findings in brain tissues and liver [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/proteome-base-fact-sheet.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/proteome-analysis-of-huntingtons-disease-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) ## [Huntingtin (HTT) Quantitation Assays Fact Sheet](https://news.cyprotex.com/sciencepool/huntingtin-htt-quantitation-assays-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 11, 2021 10:37:59 AM Download this fact sheet to learn more about Huntingtin quantitation assays including:  - Immunoassay platforms - HTT assay menu - Case studies [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/huntingtin-mhtt-protein-assay-fact-sheet.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/huntingtin-htt-quantitation-assays-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) ## [Huntingtons Disease AAV and LV Capabilities Fact Sheet](https://news.cyprotex.com/sciencepool/aav-and-lv-capabilities-for-huntingtons-disease-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 11, 2021 10:35:21 AM Download this fact sheet to learn more about Evotec's capabilities in AAV and LV application including: - Case studies - AAV production, QC and in vitro / in vivo - High quality virus production and purification [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/huntingtons-aav-lv-app.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/aav-and-lv-capabilities-for-huntingtons-disease-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) ## [Huntington's Disease Stem Cell Research Fact Sheet](https://news.cyprotex.com/sciencepool/stem-cell-research-for-huntingtons-disease-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 11, 2021 10:22:01 AM Download this fact sheet to learn more about cellular assays and stem cell research for HD including:  - Case studies - High-content screening/imaging - Biochemical assays - Specifically designed HD in vitro platforms [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/stem-cell-huntingtons-fact-sheet.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/stem-cell-research-for-huntingtons-disease-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) ## [Mutant Huntingtin Protein Assay Fact Sheet](https://news.cyprotex.com/sciencepool/mutant-huntingtin-mhtt-protein-assay-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 11, 2021 9:58:43 AM Download this fact sheet to learn more about mutant huntingtin (mHTT) protein quantitative assay including: - Antibodies used in validation - Assay parameters - Clinical studies support services [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/huntingtin-mhtt-protein-assay-fact-sheet.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/mutant-huntingtin-mhtt-protein-assay-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) ## [PhosphoScout Capabilities Fact Sheet](https://news.cyprotex.com/sciencepool/phosphoscout-capabilties-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 10, 2021 11:35:24 PM Download this fact sheet to learn more about PhosphoScout including: - Novel technologies - Workflows - Case studies [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/phosphoscout-fact-sheet.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/phosphoscout-capabilties-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) ## [High Content Image Analysis Fact Sheet](https://news.cyprotex.com/sciencepool/high-content-image-analysis-fact-sheet) Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Feb 10, 2021 2:28:14 PM Download this fact sheet to learn more about high content image analysis including: - Fingerprinting of stem cell derived cultures - Automated analysis of neuronal primary cultures - Evotec's sophisticated imaging and analysis platform  [DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/high-content-image-fact-sheet.pdf) 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/high-content-image-analysis-fact-sheet#comments-listing) Tags: [Neuroscience](https://news.cyprotex.com/sciencepool/tag/neuroscience), [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets) [Previous](https://news.cyprotex.com/sciencepool/tag/neuroscience/page/4) [All posts](https://news.cyprotex.com/sciencepool/all)