Featured in Nature, this article interviews experts, Paul Walker, Rüdiger Fritsch, and Carla Tameling, and provides the latest insights into transcriptomics and how the technology is transforming toxicology prediction.
It includes:
- an overview of the current challenges in predicting organ-specific toxicity especially DILI
- the advantages of using human cell-based models with a particular focus on 3D organoid models
- a background to transcriptomics and how advances in throughput have widened its application
- how combining transcriptomics with machine learning and artificial intelligence has increased the power of this technology in toxicology prediction