During analysis of samples from HT-ADME screening, non-specific binding can cause challenges due to accumulation within the analytical system. This can result in poor peak shape, low sensitivity, increasing back pressure/pressure spikes, carryover or system clogging.
In this poster, we focus on:
- the evaluation of the WatersTM Acquity Premier UPLC in conjunction with the Acquity Premier HSS T3 column technology which contain an inert coating specifically formulated to eliminate analyte/surface interactions
- a comparison with standard UPLC technology
- details on the benefits of using the Waters AcquityTM system in terms of chromatographic performance and sensitivity
Read our poster to learn more about our research!