| Hit & Target ID/Validation (2)

Human iPSC-Derived Mixed CNS Cells Fact Sheet

Posted by Evotec on Jun 21, 2021 12:01:21 PM

Learn more about Human iPSC-Derived Mixed CNS Cells and their advantages including:

Highly physiological neural networks
Long term synchronous network activity
Suitable as seizure liability mode

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Tags: Neuroscience, Fact Sheets, Hit & Target ID/Validation, Biologics, In vitro Biology, Toxicology & Safety

Human iPSC-Derived Cardiomyocyte Fact Sheet

Posted by Evotec on Jun 21, 2021 12:00:42 PM

Learn more about the advantages of human iPSC-derived cardiomyocytes including:

Predictive and physiological cell model
Applicable for drug development, preclinical research, and cardiac safety assessment
Quantity, consistency and efficiency for HTS

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Tags: Fact Sheets, Hit & Target ID/Validation, Biologics, In vitro Biology, Toxicology & Safety

In Vitro iPSC Research Services Fact Sheet

Posted by Evotec on Jun 21, 2021 11:59:53 AM

Learn more about in Vitro iPSC research services at Evotec including:

Robust differentiation protocols or adaptation of client protocols
High-quality production of iPSC-derived cells at large scale
Disease-relevant phenotypic read-outs for exploratory research and compound profiling/HTS
Proprietary iPSC patent portfolio in tissue and disease modeling

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Tags: Fact Sheets, Hit & Target ID/Validation, Biologics, In vitro Biology, Toxicology & Safety

Potent and Selective Agonists of Human TRPM5

Posted by Evotec on Jun 17, 2021 5:49:12 PM

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Tags: Articles & Whitepapers, Hit & Target ID/Validation, In vivo Pharmacology

AhR as a Molecular Target of the Utrophin Modulator Ezutromid

Posted by Evotec on Mar 11, 2021 8:21:57 PM

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Tags: Articles & Whitepapers, Hit & Target ID/Validation, Proteomics, Metabolomics & Biomarkers, Metabolic Disease & Complications, Rare Diseases

Potent and Selective hEP4-R Antagonist for Endometriosis Treatment

Posted by Evotec on Mar 11, 2021 8:13:31 PM

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Tags: Medicinal Chemistry, Women's health, Articles & Whitepapers, Hit & Target ID/Validation, Immunology & Inflammation

NF-κB Inducing Kinase: A Therapeutic Target for Systemic Lupus Erythematosus

Posted by Evotec on Mar 4, 2021 10:32:47 PM

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Tags: Articles & Whitepapers, Hit & Target ID/Validation, Immunology & Inflammation

Identification of Novel Selective CB2 Receptor Agonists through CADD

Posted by Evotec on Mar 2, 2021 1:00:35 PM

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Tags: Articles & Whitepapers, Hit & Target ID/Validation

Tropomyosin Receptor Kinase Inhibitors

Posted by Evotec on Mar 2, 2021 11:08:57 AM

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Tags: Articles & Whitepapers, Hit & Target ID/Validation

Advantages of Miniaturization of Calcium Flux Assay into 1536-well

Posted by Evotec on Feb 24, 2021 12:45:50 PM

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Tags: Posters, Hit & Target ID/Validation

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