Science Pool

Evotec

Recent Posts

The Discovery and Structure-Activity Evaluation of (+)-Floyocidin B and Synthetic Analogs

Posted by Evotec on Apr 20, 2022 1:08:38 PM
The emergence of multidrug-resistant M. tuberculosis makes the discovery of novel anti-tuberculosis active structures an urgent priority. This collaborative scientific article shows that (+)-floyocidin B representing the first example of a novel dihydroisoquinoline class of fungus-derived natural products, displays promising antitubercular hit properties.

LEARN MORE

Tags: Articles & Whitepapers, Anti-Infectives

Prepared for Viruses and More....

Posted by Evotec on Apr 14, 2022 5:41:39 PM

About this Webinar

In this short recording, Dr Pia Thommes, VP Anti-Infectives and Virology Therapeutic Leader discusses:

  • Current challenges in Infectious Diseases drug discovery
  • Human SARS-CoV-2 and other emerging viruses
  • Industry relevant in vivo models
  • The wider reaching consequences of the COVID pandemic

More about Dr Pia Thommes.

Pia Thommes border

Pia gained her PhD in Molecular Genetics and followed this with a postdoctoral in biochemistry, focusing on DNA replication and cell cycle. She has 12 years experience in drug discovery of antivirals at GW/GSK, 4 years work in oncology on DNA Damage Response at KuDOS/ AZ. In 2012 Pia took on a role as Scientific Operations Director at Euprotec, a specialist CRO for infectious disease, this was incorporated into the Evotec family in 2014. Currently Pia is working as VP of Anti-infectives in Alderley Park and also Therapeutic Area Lead for Virology.

Hope you enjoy the webinar

Watch the Recording Now

Tags: Videos & Webinars, In vivo Pharmacology, Anti-Infectives

Cytochrome P450 Induction Fact Sheet

Posted by Evotec on Apr 7, 2022 2:50:14 PM

Download this fact sheet to learn more about cytochrome P450 (CYP) induction including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the CYP induction assay
DOWNLOAD 

 

Tags: Fact Sheets, ADME/DMPK

Cytochrome P450 Induction: Relative Induction Score (RIS) Fact Sheet

Posted by Evotec on Apr 7, 2022 2:47:22 PM

Download this fact sheet to learn more about cytochrome P450 (CYP) relative induction score (RIS) including:

  • Background information for the CYP induction RIS method
  • Assay details and protocol summary for the CYP induction RIS method
  • Data generated in the CYP induction RIS assay
DOWNLOAD 

 

Tags: Fact Sheets, ADME/DMPK

Hepatocyte Stability Fact Sheet

Posted by Evotec on Apr 7, 2022 1:20:01 PM

Download this fact sheet to learn more about hepatocyte stability including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the hepatocyte stability assay
DOWNLOAD 

 

Tags: Fact Sheets, ADME/DMPK

Safety Prediction and Transcriptomics Fact Sheet

Posted by Evotec on Apr 7, 2022 12:26:10 PM

Learn more about the use of transcriptomics in safety prediction including:

  • the challenges in translation from animals to humans, and how human cell-based models are now being routinely used in toxicology
  • how transcriptomic analysis is showing promise in enhancing safety prediction and providing additional mechanistic information
  • an overview of how Cyprotex, and parent company Evotec, are offering a fully customised end-to-end in vitro transcriptomics service using the latest next generation sequencing technology (RNA-seq) and a leading bioinformatics platform
  • the use of sophisticated machine learning and artificial intelligence to interpret the large and complex datasets
DOWNLOAD

Tags: Fact Sheets, Toxicology & Safety

Deutsche Biotechnologietage 2022

Posted by Evotec on Apr 7, 2022 12:14:45 PM

Deutsche Biotechnologietage is a German language only conference. The following information regarding the conference is in German for this reason.

Datum: 4. - 5. Mai 2022

Ort: CCH Congress Center, Hamburg, Deutschland 

Vortragende: Werner Lanthaler, Thomas Hanke, Sandra Lubitz, Christiane Honisch

Teilnehmer des Business Development: Daniel Gliesche, Sneha Kumar, Laurie Sarrat, Margit Wissenbach

 

Evotec ist Hauptsponsor der diesjährigen Deutschen Biotechnologietage und wird seine neuste Forschung vor Ort präsentieren.

 

 

werner

Eröffnungsplenum

Dr. Werner Lanthaler, CEO

Mittwoch, 4. Mai | 10:00 Uhr

Sandra Lubitz

Symposium

Induzierte pluripotent Stammzellen - Wo stehen wir heute bei der Anwendung dieser Klasse von Advanced Therapy Medicinal Products?

Dr. Sandra Lubitz, VP Head of iPSC

Mittwoch, 4. Mai | 13:00 – 14:10 Uhr

Christiane Honisch_rsz

 

Luncheon

E.MPD Evotec's Molecular Patient Database

Dr. Christiane Honisch, SVP Head of Diagnostics

Donnerstag, 5. Mai | 12:50 – 13:20 Uhr

Thomas Hanke_Evotec-1

 

Symposium

Alles nur Establishment? Wie agil und frisch ist die Biotechnologiebranche in Deutschland?

Dr. Thomas Hanke, EVP Head of Academic Partnerships

 

Donnerstag, 5. Mai | 14:00 - 15:10 Uhr

 

Wenn Sie Interesse haben sollten sich mit uns in Hamburg zu treffen, setzen Sie sich bitte über das unten stehende Formular mit uns in Verbindung, damit wir einen Termin vereinbaren können.

Erfahren Sie mehr über die Deutsche Biotechnologietage 2022.

Tags: Events, Evotec

EMBO Workshop - RNA: Structure meets function

Posted by Evotec on Apr 7, 2022 10:13:23 AM

Date: 27 June - 1 July 2022

Location: Skåvsjöholm, Åkersberga, Sweden

Attending: Anne Tuukkanen

 

Join Evotec at EMBO Workshop about RNA: Structure meets function!

 

If you wish to meet with us in Sweden, get in touch via the form below, we will be happy to arrange a meeting.

Learn more about the EMBO Workshop.

Tags: Events, Evotec

8th NovAliX Conference

Posted by Evotec on Apr 7, 2022 10:05:24 AM

Date: 9-11 May 2022

Location: Holiday Inn Munich - City Center, Germany

Attending: Anne Stinn

 

Join Evotec at the 8th NovAliX Conference on Biophysic in Drug Discovery in Munich.

 

If you wish to meet with us in Munich, get in touch via the form below, we will be happy to arrange a meeting.

Learn more about the NovAliX Conference 2022.


Tags: Events, Evotec

3rd International Conference on Hydrogen Deuterium Exchange Mass Spectrometry

Posted by Evotec on Apr 7, 2022 10:00:15 AM

Date: 24-26 April 2022

Location: The Crick Institute, London, UK

Attending: Jasmin Duelfer, Florian-Alexander Herbst

 

Join Evotec at the 3rd International Conference on Hydrogen Deuterium Mass Spectrometry in London.

 

If you wish to meet with us in London, get in touch via the form below, we will be happy to arrange a meeting.


Learn more about the 3rd International Conference.

Tags: Events, Evotec