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E.SOLVE is Evotec's solution to accelerate your journey to the clinic supporting your formulation strategy as early as possible from discovery to market approval.

Download this fact sheet to learn more about how E.SOLVE's full range of approaches improve solubilization and bioavailability to ensure that your API can progress through the drug discovery development pipeline faster.

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Tags: IND Enabling, Fact Sheets, Formulation & CMC, Toxicology & Safety

Regulated ADMET Services Fact Sheet

Posted by Evotec on Mar 2, 2022 1:34:27 PM

Download this fact sheet to learn more about our regulatory ADMET services including:

Full support of development projects to fulfill and anticipate regulatory requirements
Accelerated development process with a full vision through all drug development phases up to filing
Dynamic team of expert scientists capable of handling projects of any complexity in regulated environment
Full integration with in-house bioanalytical and safety assessment groups
Tailored studies and programs based on specific client needs

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Tags: Fact Sheets, ADME/DMPK, IND Enabling Studies/Preclinical Development, Toxicology & Safety

INDiGO-Select Fact Sheet

Posted by Evotec on Mar 2, 2022 1:34:15 PM

Learn more about how our INDiGO-Select services help in profiling and selecting your optimal clinical development candidate with:

Enhanced quality profile, speed of delivery, and probability of success of clinical candidates
Early identification of developability gaps and liabilities in selection process, enabling thorough
de-risking of your candidate with flexible advanced lead optimization approaches
Managed by skilled discovery scientists and complemented by experienced drug development
experts in CMC and preclinical development all under one roof

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Tags: INDiGO, Fact Sheets, IND Enabling Studies/Preclinical Development, Toxicology & Safety, Clinical Development

Clinical Services Fact Sheet

Posted by Evotec on Mar 2, 2022 1:12:17 PM

Learn more about our clinical services platform including:

Fully integrated drug development services supporting preclinical and clinical needs,
up to regulatory approval and commercial phases
Clinical supply suitable from First in Human to Phase III, fully GMP-compliant and
with capacity to handle active ingredients classified up to OEB5 (OEL>0.5 µg/m³)
Additional capabilities such as API, formulation development, sample management, PK and statistical analyses, and metabolism

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Tags: INDiGO, Fact Sheets, IND Enabling Studies/Preclinical Development, Clinical Development

NE-ADME (New Era of ADME & Beyond)

Posted by Evotec on Mar 2, 2022 10:05:18 AM

Date: 16 June 2022

Location: Novartis Institutes for BioMedical Research, Cambridge, MA

Attendees: Ralf Geiben Lynn, Sravani Adusumalli & Janice Lau

Presenting: Sravani Adusumalli - Development of a High-Throughput and Efficient Automated Workflow to Determine Blood to Plasma Ratio

Learn more about NE-ADME (New Era of ADME & Beyond)

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Tags: Events, Cyprotex

Applied Pharmaceutical Toxicology 2022

Posted by Evotec on Mar 2, 2022 10:03:53 AM

Date: 10-12 May 2022

Location: Vertex Pharmaceuticals, Boston, MA

Attendees: Ralf Geiben Lynn & Chris Strock

Presenting: Identifying Seizures with MEA: Complementary Human and Rat Neuronal models enhance predictivity & High throughout RNA-seq profiling of 3D liver organoids to predict Drug Induced Liver Injury (DILI). - Chris Strock

Learn more about Applied Pharmaceutical Toxicology 2022

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Tags: Events, Cyprotex

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