Date: 24-27 May 2022
Location: Royal Dublin Society, Dublin, Ireland
Attending: Oliver Casamitjana
Evotec will be showcasting our research at the SLAS Europe 2022 Conference and Exhibition on May 24-27 in Ireland.
If you wish to meet with us in Dublin, get in touch via the form below, we will be happy to arrange a meeting.
Date: 10-11 May 2022
Location: etc.venues, London, UK
Attending: Werner Lanthaler
Our scientific program
The Next Phase Of Europe’s Booming Biotech Ecosystem – Building Global Biotech Leaders, Financing Next Wave Innovation And Joining The Dots Between Clusters
Dr. Werner Lanthaler, Chief Executive Officer
Tuesday, May 10th | 9:30 am
If you wish to meet with us in London, get in touch via the form below, we will be happy to arrange a meeting.
Date: 26 - 27 April 2022
Location: etc.venues, London, UK
Attending: Florence Eustache, Shweta Singh Upadhyay
If you wish to meet with us in London, get in touch via the form below, we will be happy to arrange a meeting.
Date: 25-27 April 2022
Location: Wyndham Boston Beacon Hill, Boston, Massachusetts, USA
Attending: Kara Carter
If you wish to meet with us in Boston, get in touch via the form below, we will be happy to arrange a meeting.
Learn more about the 2nd Chronic HBV Drug Development Summit
Date: 28 - 31 March 2022
Location: Virtual
Attending: Jason Brown, Florence Eustache, Christelle Dagoneau, Bernd Muehlenweg
Evotec is attending this year's Bio-Europe Spring with our Just-Evotec Biologics colleagues.
Bernd Muehlenweg, SVP Innovate Strategic Initiatives
Tuesday, March 29 | 4:00 pm - 5:00 pm
Tags: Events, Evotec, Just Evotec Biologics
In this webinar, John Barker, SVP Global Head of Protein Sciences discusses bacterial infections and global health within anti-infectives. John gave this talk at the Oxford Global Discovery UK event in October 2021.
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John Barker, PhD FRSB Senior Vice President, Global Head of Protein Sciences | Evotec Currently responsible for more than 150 scientists across four sites, Princeton NJ, Abingdon UK, Toulouse and Hamburg. Team delivering Protein Production, Structural Biology and Cellular Sciences both internally and to Evotec’s partnerships. Over the past 18 years built from the ground up the current Evotec structural biology unit, now with more than 30 PhD scientists, one of the largest units in industry. Supporter of UK industry as the Industrial Life Science representative on the Diamond Scientific Advisory Board. John has worked on more than 40 collaborations across a range of drug discovery projects including multiple structure and fragment guided programmes in all therapeutic areas. |
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Tags: Videos & Webinars, Structural Biology & Protein Science, Anti-Infectives
Date: 23rd - 26th April 2022
Location: Lisbon, Portugal
Attending: Stephane Vandenabeele, Nadir Bessila, Pia Thommes, Francesca Bernardini, Greg Whelan, Sebastien Coyne
ECCMID is Europe's largest Clinical Microbiology & Infectious Diseases event which unites experts from numerous fields to present their latest findings, guidelines, and research to an international audience. This year, the congress will feature a hybrid format to facilitate an onsite and online participation for attendees, allowing remote and face-to-face opportunities.
Connect with our scientific specialists at booth #2-32.3 and don't forget to include our poster presentation in your ECCMID itinerary!
Our scientific program
Poster 04944 - APC148: A new first-in-class modular synthetic metallo-β-lactamase inhibitor reverses carbapenem resistance in Gram-negative pathogens in vitro and in vivo in preclinical studies.
If you wish to meet with us in Lisbon or virtually outside of the event, get in touch via the form below, we will be happy to arrange a meeting.
The development of novel drugs is requiring much more than preclinical and clinical studies. Once scientists have identified a biological structure they want to block or to engage with, they begin screening for compounds that are able to fulfill this task. However, before they can even start this screening process, which can involve tens of thousands of compounds, these molecules have to be synthesized or extracted, purified, collected, stored, catalogued and tracked so that they can be made available to be processed.
Compound management involves receiving and registering compounds from any external sources, organizing their long-term storage in a safe and controlled environment. For the acquisition of new molecules, Evotec has established a platform collecting and evaluating catalogs of compound providers. Compounds not yet available in Evotec’s collection can be sourced via this platform and added to the collection or made available to the customer as required. These compounds must be stored in a dedicated space under the right conditions in terms of temperature, humidity and other factors which could influence their stability. Access is restricted to authorized personnel to avoid accidental or deliberate manipulation of the samples. This requires a lot of logistics, regular controls, and supervision.
To ensure high quality, safe, and speedy delivery of compounds, Evotec has established six compound management teams located in Europe and the US. Its main sites in Toulouse (France), and in Branford, (CT, USA), handle most of the samples received by Evotec, which include small molecules as well as biologicals. Overall, Evotec’s six compound management sites can store over 13 million compound containers under optimum conditions, and are able to process and deliver over 53 millions samples per year. The Company’s high quality compound storage and fast turnaround time, are based on robust automated technology, a highly sophisticated laboratory information management system (LIMS), and secure data management. All sites operate under quality management and internal auditing principles. The main sites have developed a Business Continuity plan to ensure complete protection for our customers. Evotec is using Titian's Mosaic software, the leading software solution for sample management, providing for a full audit trail and complete sample life cycle tracking. Every single sample carries a unique identifier barcode and the LIMS system is able to track each operations across all sample management processes, ensuring refill of depleted substances are automatically enacted. The system has in-built redundancy to protect the data against critical loss.
Once ordered, delivery of individual compounds or compound collections to customers and partners are organised in a short time frame ensuring the right format, concentration, and volume of substances are prepared. Samples are being shipped all over the world. Evotec also takes care of choosing the right parcel services, as frozen or temperature-sensitive substances need to be shipped under specific controlled conditions to protect temperature shift. In addition, Evotec’s dedicated logistic team has expertise in documentation requirements, tariff classification, and import/export customs requirements to ensure compounds shipped can travel through customs without delays linked to incomplete paperwork.
Evotec is continuously investing in state-of-the-art technologies to keep its compound management tools up to date. As an example, it invested in acoustic sample management, where liquids are transferred via acoustic sound waves, creating a droplet at the liquid’s surface. This technology increases flexibility, throughput and reduces compound consumption. The Company has been building screening libraries since 2004 and is serving a broad variety of customers ranging from academia, non-profit organizations to medium-sized biotech and big pharma. Apart from ordering and receiving compounds, customers are also able to enter collaborations in which Evotec stores and manages their proprietary compound libraries and collections. This enables large companies as well as fast-growing SMEs to save space and costs while gaining more flexibility.
As a result, customers profit from Evotec’s expertise, state of the art investment with large storage capacity and capabilities, its experienced staff and the inbuilt security safeguarding quality and availability of valuable compounds. Thereby, Evotec’s compound libraries and management tools significantly contribute to the success of drug discovery research projects as well as to medicinal product development.
Tags: Blog, Sample Management
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