Diverse modalities are typically defined as those molecules which sit outside the rule of five characteristics for small molecules. These diverse modalities are often termed beyond the rule of five molecules, and include peptides, targeted protein degraders, oligonucleotides including ASOs, siRNAs and oligoconjugates, and proteins and monoclonal antibodies. Due to their characteristics, diverse modalities may require specialist assay design or analytical methods.
Cyprotex has expertise in assessing the ADME-Tox for various different types of diverse modalities to ensure robust data are generated.
Read our fact sheet to learn more about our services for assessing diverse modalities.