Science Pool

Cytochrome P450 Time Dependent Inhibition (Single Point) Fact Sheet

Posted by Evotec on Sep 1, 2021 3:14:19 PM

Learn more about the cytochrome P450 time dependent inhibition (CYP TDI) single point assay including:

  • background information
  • assay details and protocol summary
  • assay data generated in the CYP TDI single point assay
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Tags: Fact Sheets, ADME/DMPK

Cytochrome P450 Time Dependent Inhibition (IC50 Shift) Fact Sheet

Posted by Evotec on Sep 1, 2021 3:13:19 PM

Learn more about the cytochrome P450 time dependent inhibition (CYP TDI) IC50 shift assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the CYP TDI IC50 shift assay
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Tags: Fact Sheets, ADME/DMPK

Cytochrome P450 Time Dependent Inhibition (kinact/KI) Fact Sheet

Posted by Evotec on Sep 1, 2021 3:12:26 PM

Learn more about the cytochrome P450 time dependent inhibition (CYP TDI) kinact/KI assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the CYP TDI kinact/KI  assay
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Tags: Fact Sheets, ADME/DMPK

Cytochrome P450 Inhibition Ki Fact Sheet

Posted by Evotec on Sep 1, 2021 3:11:33 PM

Learn more about CYP inhibition (Ki) including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the CYP inhibition (Ki) assay
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Tags: Fact Sheets, ADME/DMPK

Blood Binding Fact Sheet

Posted by Evotec on Sep 1, 2021 3:09:22 PM

Learn more about the whole blood binding assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the whole blood binding assay
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Tags: Fact Sheets, ADME/DMPK

Breast Cancer Resistance Protein Substrate Identification Fact Sheet

Posted by Evotec on Sep 1, 2021 3:07:22 PM

Learn more about the breast cancer resistance protein (BCRP) substrate identification assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the BCRP substrate identification assay
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Tags: Fact Sheets, ADME/DMPK

Hepatic Uptake Fact Sheet

Posted by Evotec on Sep 1, 2021 2:58:00 PM

Learn more about the hepatic uptake assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the hepatic uptake assay
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Tags: Fact Sheets, ADME/DMPK

Log D Shake Flask Fact Sheet

Posted by Evotec on Sep 1, 2021 2:54:33 PM

Learn more about the Log D shake flask assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the Log D shake flask assay
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Tags: Fact Sheets, ADME/DMPK

Parallel Artificial Membrane Permeation Assay Fact Sheet

Posted by Evotec on Sep 1, 2021 2:49:30 PM

Learn more about parallel artificial membrane permeation assay (PAMPA) including:

  • Background information
  • Assay details and protocol summary
  • Data generated in PAMPA
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Tags: Fact Sheets, ADME/DMPK

Plasma Stability Fact Sheet

Posted by Evotec on Sep 1, 2021 2:45:02 PM

Learn more about the plasma stability assay including:

  • Background information
  • Assay details and protocol summary
  • Data generated in the plasma stability assay
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Tags: Fact Sheets, ADME/DMPK