Science Pool

Transporter DDI - An Evaluation of Approaches and Methodology

Posted by Evotec on Feb 12, 2021 5:31:58 PM

Due to an aging population, polypharmacy is increasing. Drug-drug interactions account for 5% of UK hospital admissions, and are a particular concern for common co-meds such as statins.

In this presentation, we focus on:

  • a background to drug-drug interactions (DDI)
  • the use of the mechanistic static models in the prediction of transporter-mediated DDI
  • a comparison of the different published models and their performance 

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Tags: Presentations, ADME/DMPK