Science Pool

Gene therapy has evolved as an attractive modality to tackle and/or even cure a broad range of diseases. EVOgenes is built on a team with long-standing pharma expertise in various gene therapy-related technologies and indications.

Take a look at our factsheet to discover the broad spectrum of state-of-the-art services enabling gene therapy product development we offer.

Date: 18th - 20th October 2023

Location: Espace Centenaire, Paris 

Attending: Tim Potter

Learn more about The 35th GMP Symposium

• The genotoxic potential is one of the major risks associated to potential pitfalls in drug development.
• True positive results in the genotoxicity screening observed during the Lead Optimization phase not always represent a showstopper, but need to be carefully characterized.
• In this scenario, the toxicologist could provide a strategy supporting the next IND enabling phase by adopting the most effective risk management to allow the highest success rate possible.
• The process proposed can be adapted to any scenario, and provides data supporting the risk assessment ensuring the lowest attrition and the ethical use of animals.

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Read our latest poster on Differentiated transcriptomic signatures detectable in primary human hepatocytes transduced by AAV-based vectors: A potential enabler for in vitro safety profiling.

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Rapid turnaround is essential for ADME-Tox services, especially during drug discovery. However, turnaround time for the assay isn’t the only consideration. The time required to prepare the quotation may delay the scheduling of the assay and, in turn, the study start date.

The new Cyprotex e-Store provides a solution to this. Registered users of the e-Store are able to view instant pricing for a comprehensive range of ADME-Tox services. As well as having access to detailed protocols and the latest editions of our educational guides, users also benefit from special offers only available through the e-Store.

Online ordering is simple. Previous orders can be tracked through the e-Store and it is easy to re-order your favourite assays. All of this information can be accessed outside business hours. A range of payment options are available on the e-Store including credit card, existing purchase order or invoice. These features allow services to be ordered and scheduled the same day so saving you time.

Despite this automated approach, you are still supported by a dedicated scientific study manager and account manager who are on-hand to guide you at all stages of your study.

Want to learn more?

Explore the Cyprotex e-Store