---
title: | Proteomics, Metabolomics & Biomarkers (2)
description: Proteomics, Metabolomics & Biomarkers |  (2)
---

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# Science Pool

## [Ligand Binding Assays Fact Sheet](https://news.cyprotex.com/sciencepool/ligand-binding-assays-fact-sheet)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Dec 16, 2021 12:36:06 PM

Learn more about our ligand binding assays and how they can support biological drug testing in a regulated environment, including:

- Regulated bioanalysis
- Immunogenicity
- Immunotoxicity
- Biomarkers (safety and efficacy)
- Clinical Pathology
- Sample Management
- Additional activities

[DOWNLOAD](https://news.cyprotex.com/hubfs/Sciencepool/Fact%20sheets/Evotec%20Fact%20Sheets/pcd-ligand-binding-assay.pdf)

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/ligand-binding-assays-fact-sheet#comments-listing)

 Tags: [Fact Sheets](https://news.cyprotex.com/sciencepool/tag/fact-sheets), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers), [IND Enabling Studies/Preclinical Development](https://news.cyprotex.com/sciencepool/tag/ind-enabling-studies-preclinical-development), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety), [Sample Management](https://news.cyprotex.com/sciencepool/tag/sample-management)

## [Machine Learning using Omics Data](https://news.cyprotex.com/sciencepool/machine-learning-using-omics-data)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Nov 26, 2021 1:33:50 PM

This article forms a book chapter in Artificial Intelligence in Drug Design.

In this review article, we discuss the use of machine learning approaches in large omics studies

The chapter includes:

- an overview of the typical analysis of an omics dataset using machine learning
- demonstration of how to build a model predicting drug-induced liver injury (DILI) using transcriptomics data
- best practices and pitfalls to consider during initial data exploration and model training through to validation and analysis of the final model

[LEARN MORE](https://link.springer.com/protocol/10.1007/978-1-0716-1787-8_18)

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/machine-learning-using-omics-data#comments-listing)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers), [Toxicology & Safety](https://news.cyprotex.com/sciencepool/tag/toxicology-safety)

## [How to Build an Innovative Pipeline- Dr. Cord Dohrmann, Evotec](https://news.cyprotex.com/sciencepool/how-to-build-an-innovative-platform)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Nov 5, 2021 4:35:42 PM

### Fireside Chat at BIO-Europe 2021

Evotec Chief Scientific Officer, Dr Cord Dohrmann, talks to Dr Hubert Birner, Managing Partner at TVM Capital Life Sciences, about how Evotec has built an impressive and innovative platform.

[WATCH NOW](https://knect365.wistia.com/medias/mreepvg8aa)

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/how-to-build-an-innovative-platform#comments-listing)

 Tags: [Videos & Webinars](https://news.cyprotex.com/sciencepool/tag/videos-webinars), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers)

## [Time-Resolved Ubiquitinome Profiling by DIA-MS Reveals USP7 Targets](https://news.cyprotex.com/sciencepool/time-resolved-ubiquitinome-profiling-by-dia-ms-reveals-usp7-targets)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Oct 4, 2021 5:22:21 PM

Mass spectrometry (MS)-based ubiquitinomics allows a system-level understanding of ubiquitin signalling. 

In this publication, we focus on:

- a background to ubiquitinome profiling
- presentation of a scalable and robust workflow for deep and precise *in vivo* ubiquitinome profiling using DIA-MS (data-independent acquisition mass spectrometry) and neural network based data processing
- comprehensive mapping of substrates of deubiquitinase USP7, an anticancer drug target known to regulate tumour suppressor p53
- application of the method including rapid mode of action profiling of candidate drugs targeting deubiquitinases or ubiquitin ligases 

[LEARN MORE](https://www.nature.com/articles/s41467-021-25454-1)

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/time-resolved-ubiquitinome-profiling-by-dia-ms-reveals-usp7-targets#comments-listing)

 Tags: [Oncology](https://news.cyprotex.com/sciencepool/tag/oncology), [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers)

## [Fast and Straightforward Biomarker Identification in PanHunter](https://news.cyprotex.com/sciencepool/panhunter-software-demo)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Jul 2, 2021 2:44:13 PM

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/panhunter-software-demo#comments-listing)

 Tags: [Videos & Webinars](https://news.cyprotex.com/sciencepool/tag/videos-webinars), [In vitro Biology](https://news.cyprotex.com/sciencepool/tag/in-vitro-biology), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers)

## [AhR as a Molecular Target of the Utrophin Modulator Ezutromid](https://news.cyprotex.com/sciencepool/ahr-as-a-molecular-target-of-the-utrophin-modulator-ezutromid)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Mar 11, 2021 8:21:57 PM

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/ahr-as-a-molecular-target-of-the-utrophin-modulator-ezutromid#comments-listing)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Hit & Target ID/Validation](https://news.cyprotex.com/sciencepool/tag/hit-target-id-validation), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers), [Metabolic Disease & Complications](https://news.cyprotex.com/sciencepool/tag/metabolic-disease-complications), [Rare Diseases](https://news.cyprotex.com/sciencepool/tag/rare-diseases)

## [A Multidisciplinary Approach to Gene Therapy Development](https://news.cyprotex.com/sciencepool/a-multidisciplinary-approach-to-gene-therapy-development)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Mar 11, 2021 8:19:11 PM

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/a-multidisciplinary-approach-to-gene-therapy-development#comments-listing)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Biologics](https://news.cyprotex.com/sciencepool/tag/biologics), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers), [Rare Diseases](https://news.cyprotex.com/sciencepool/tag/rare-diseases)

## [Can Biomarkers help us to Develop Personalised Medicine Faster?](https://news.cyprotex.com/sciencepool/can-biomarkers-help-us-to-develop-personalised-medicine-faster)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Mar 8, 2021 10:47:13 PM

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/can-biomarkers-help-us-to-develop-personalised-medicine-faster#comments-listing)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers)

## [How Proteomics Boosts the Discovery of Novel Drugs and Biomarkers](https://news.cyprotex.com/sciencepool/how-proteomics-boosts-the-discovery-of-novel-drugs-and-biomarkers)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Mar 8, 2021 10:41:17 PM

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/how-proteomics-boosts-the-discovery-of-novel-drugs-and-biomarkers#comments-listing)

 Tags: [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers)

## [Phosphorylation Signatures Predict Response to Dasatinib](https://news.cyprotex.com/sciencepool/phosphorylation-signatures-predict-response-to-dasatinib)

 Posted by [Evotec](https://news.cyprotex.com/sciencepool/author/evotec) on Mar 6, 2021 2:32:48 PM

 0 Comments [Click here to read/write comments](https://news.cyprotex.com/sciencepool/phosphorylation-signatures-predict-response-to-dasatinib#comments-listing)

 Tags: [Oncology](https://news.cyprotex.com/sciencepool/tag/oncology), [Articles & Whitepapers](https://news.cyprotex.com/sciencepool/tag/articles-whitepapers), [Proteomics, Metabolomics & Biomarkers](https://news.cyprotex.com/sciencepool/tag/proteomics-metabolomics-biomarkers)

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