Science Pool

3D Cell Models DDup #12

Posted by Evotec on Mar 10, 2022 11:38:33 AM

The 12th edition of our Drug Discovery Update (DDup) provides insights into exciting new developments in 3D cell models including microtissues, organoids and organ-on-a-chip technology.

In this edition, it covers:

  • an introduction to 3D cellular models
    • the need for better models to improve translation from in vitro to in vivo
    • the relevance of 3D cellular models to kidney disease modelling and drug induced toxicity prediction
  • an overview of Evotec's 3D in vitro platforms
    • glomerulus-on-a-chip to study kidney disease
    • kidney organoids to study polycystic kidney disease
    • organ microtissues to predict drug-induced toxicity
  • interviews with experts Dr Christodoulos Xinaris, Dr Reiner Class, Dr Magali Ferro and Dr Stephanie Ryder

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Tags: Kidney diseases, Articles & Whitepapers, Toxicology & Safety, Metabolic Disease & Complications

Metabolic and Kidney Disease Long Term Vision Fact Sheet

Posted by Evotec on Mar 8, 2021 10:30:59 PM

Learn more about Evotec's long term vision in Kidney Disease therapeutics including:

  • Molecular patient databases
  • Patient derived disease models
  • Molecular profiles turned biomarkers
  • Evotec's footprint in chronic kidney disease
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Tags: Kidney diseases, Fact Sheets, Metabolic Disease & Complications

Inhibition of NF-kB Inducing Kinase in IFNα-accelerated Lupus Nephritis

Posted by Evotec on Mar 5, 2021 5:36:55 PM

Tags: Kidney diseases, Articles & Whitepapers, In vivo Pharmacology, Immunology & Inflammation, Metabolic Disease & Complications

Identifying Regulators of Kidney Fibrosis

Posted by Evotec on Mar 4, 2021 10:51:10 PM

Tags: Kidney diseases, Articles & Whitepapers, Metabolic Disease & Complications

Drug Discovery Insight: Evotec and Bayer Partner to Fight Kidney Diseases

Posted by Evotec on Mar 4, 2021 9:18:00 PM

Tags: Kidney diseases, Articles & Whitepapers, Metabolic Disease & Complications

Targeting the Podocyte to Treat Glomerular Kidney Disease

Posted by Evotec on Mar 2, 2021 12:47:18 PM

Tags: Kidney diseases, Articles & Whitepapers, Metabolic Disease & Complications

Kidney Diseases 2.0 DDup #7

Posted by Evotec on Feb 16, 2021 10:40:41 PM

Tags: Kidney diseases, Articles & Whitepapers, Metabolic Disease & Complications

Kidney Diseases DDup #3

Posted by Evotec on Feb 16, 2021 10:34:56 PM

Tags: Kidney diseases, Articles & Whitepapers, Metabolic Disease & Complications