Tags: Videos & Webinars, In vitro Biology, Toxicology & Safety
Learn more about Human iPSC-Derived Mixed CNS Cells and their advantages including:
Tags: Neuroscience, Fact Sheets, Hit & Target ID/Validation, Biologics, In vitro Biology, Toxicology & Safety
Learn more about the advantages of human iPSC-derived cardiomyocytes including:
Tags: Fact Sheets, Hit & Target ID/Validation, Biologics, In vitro Biology, Toxicology & Safety
Learn more about in Vitro iPSC research services at Evotec including:
Tags: Fact Sheets, Hit & Target ID/Validation, Biologics, In vitro Biology, Toxicology & Safety
Cardiotoxic drugs can display acute alteration in the mechanical function of the myocardium (functional changes) or morphological damage to cardiomyocytes and/or loss of viability (structural changes).
In this poster, we focus on:
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Tags: Posters, IND Enabling Studies/Preclinical Development, Toxicology & Safety
Drug-induced mitochondrial dysfunction has been associated with organ toxicity and drug withdrawal. Highly specific and sensitive in vitro assays have been developed to predict mitochondrial dysfunction.
In this publication, we focus on:
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Drug-induced liver injury (DILI) is a leading cause of drug failure due to poor translation between traditional preclinical animal models and human clinical outcome. More sophisticated human in vitro cell-based models with multiparametric endpoints are now being developed to improve DILI prediction.
In this review article, we focus on:
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It is almost 50 years since MEA was first developed, however, the power of this technology in toxicology testing has only just been realised due to the introduction of the multi-well MEA allowing for its utility in high throughput
analysis.
In this whitepaper, we focus on:
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Tags: Neuroscience, Articles & Whitepapers, Toxicology & Safety
Tags: Articles & Whitepapers, ADME/DMPK, Toxicology & Safety