| Fact Sheets (3)

Polymerase Chain Reaction Services Fact Sheet

Posted by Evotec on Dec 16, 2021 6:24:35 PM

Learn more about Evotec’s polymerase chain reaction (PCR) services including:

Therapeutic modalities
Sample management capabilities
PCR applications
Quantitative real time PCR (qPCR) and reverse transcription qPCR (RT-qPCR) applications, including copy number estimation assays, gene expression profiling and genotyping assaysRegulated PCR services

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Tags: Fact Sheets, Proteomics, Metabolomics & Biomarkers, IND Enabling Studies/Preclinical Development, Sample Management

Ligand Binding Assays Fact Sheet

Posted by Evotec on Dec 16, 2021 12:36:06 PM

Learn more about our ligand binding assays and how they can support biological drug testing in a regulated environment, including:

Regulated bioanalysis
Immunogenicity
Immunotoxicity
Biomarkers (safety and efficacy)
Clinical Pathology
Sample Management
Additional activities

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Tags: Fact Sheets, Proteomics, Metabolomics & Biomarkers, IND Enabling Studies/Preclinical Development, Toxicology & Safety, Sample Management

Pharmacokinetic Prediction Fact Sheet

Posted by Evotec on Sep 9, 2021 5:52:45 PM

Learn more about human pharmacokinetic prediction including:

background information on the predictive model
in vitro ADME data and structural data requirements for PK prediction
data delivered for the PK prediction
validation data for the predictive model

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Tags: Fact Sheets, ADME/DMPK, Modelling and Simulation

Brain Tissue Binding Fact Sheet

Posted by Evotec on Sep 1, 2021 3:17:35 PM

Learn more about the brain tissue binding assay including:

Background information
Assay details and protocol summary
Data generated in the brain tissue binding assay

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Tags: Fact Sheets, ADME/DMPK

Cytochrome P450 Time Dependent Inhibition (IC50 Shift) Fact Sheet

Posted by Evotec on Sep 1, 2021 3:13:19 PM

Learn more about the cytochrome P450 time dependent inhibition (CYP TDI) IC₅₀ shift assay including:

Background information
Assay details and protocol summary
Data generated in the CYP TDI IC₅₀ shift assay

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Tags: Fact Sheets, ADME/DMPK

Chronic Exposure Nephrotoxicity Assay Fact Sheet

Posted by Evotec on Sep 1, 2021 3:10:26 PM

Learn more about our chronic exposure nephrotoxicity assay including:

Background information
Assay details and protocol summary
Data generated in the chronic exposure nephrotoxicity assay

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Tags: Fact Sheets, Toxicology & Safety

Blood Binding Fact Sheet

Posted by Evotec on Sep 1, 2021 3:09:22 PM

Learn more about the whole blood binding assay including:

Background information
Assay details and protocol summary
Data generated in the whole blood binding assay

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Tags: Fact Sheets, ADME/DMPK

Apoptosis and Necrosis Fact Sheet

Posted by Evotec on Sep 1, 2021 3:06:09 PM

Learn more about our apoptosis and necrosis assay including:

Background information
Assay details and protocol summary
Data generated in the apoptosis and necrosis assay

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Tags: Fact Sheets, Toxicology & Safety

3D Hypertrophy and Cardiotoxicity Fact Sheet

Posted by Evotec on Sep 1, 2021 3:05:12 PM

Learn more about our 3D combined hypertrophy and cardiotoxicity assay including:

Background information
Assay details and protocol summary
Data generated in the3D combined hypertrophy and cardiotoxicity assay

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Tags: Fact Sheets, Toxicology & Safety

GreenScreen HC Genotoxicity Fact Sheet

Posted by Evotec on Sep 1, 2021 3:00:35 PM

Learn more about the GreenScreen HC genotoxicity assay including:

Background information
Assay details and protocol summary
Data generated in the GreenScreen HC genotoxicity assay

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Tags: Fact Sheets, Toxicology & Safety

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